A mathematical model for dorsal closure

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A mathematical model for dorsal closure.

During embryogenesis, drosophila embryos undergo epithelial folding and unfolding, which leads to a hole in the dorsal epidermis, transiently covered by an extraembryonic tissue called the amnioserosa. Dorsal closure (DC) consists of the migration of lateral epidermis towards the midline, covering the amnioserosa. It has been extensively studied since numerous physical mechanisms and signaling ...

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ژورنال

عنوان ژورنال: Journal of Theoretical Biology

سال: 2011

ISSN: 0022-5193

DOI: 10.1016/j.jtbi.2010.09.029